Flea and tick medicines

Flea and tick medicines are used to help manage fleas and ticks in dogs and cats. Discuss the product form and label instructions with your veterinarian. Many flea and tick collars, spot-ons and shampoos are EPA-registered pesticides, so FDA animal drug report data does not describe every flea and tick product. The National Pesticide Information Center is a resource for EPA-registered products.

The linked ingredient pages bring together FDA report counts, signs reported after an ingredient, and Green Book product names where available. FDA approves animal drugs and lists them in the Green Book. Brand names are masked in FDA’s public report data; Green Book names do not identify which products the reports concern.

Reports do not prove cause. Counts depend on use and reporting, so they cannot estimate risk or compare products. Use these pages to prepare questions, rather than to rank treatments. Talk to your veterinarian before starting, stopping or changing a medicine. If your pet has an emergency, call your veterinarian or an emergency clinic.

• Afoxolaner
• Fluralaner
• Sarolaner
• Lotilaner
• Esafoxolaner
• Nitenpyram
• Spinosad
• Selamectin
• Fipronil
• Imidacloprid
• Permethrin
• Flumethrin

These links do not recommend a medicine. Discuss treatment choices with your veterinarian.