Pet Recall Facts

Ingredients / Cefpodoxime Proxetil

Cefpodoxime Proxetil: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

4,209Total reports
4,017Dog reports
86Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

200423
200596
2006113
2007141
2008138
200988
201095
2011113
2012238
2013247
2014264
2015289
2016322
2017291
2018226
2019188
2020166
2021150
2022134
2023161
2024248
2025329
2026149

Species named in reports

Dog4,017
Not given99
Cat86
Human6
Horse1

Signs reported after Cefpodoxime Proxetil

Vomiting730
Lethargy (see also Central nervous system depression in Neurological)589
Anorexia385
Diarrhoea333
Lack of efficacy - NOS316
Other abnormal test result NOS265
Elevated alanine aminotransferase (ALT)260
Emesis256
Death by euthanasia237
Seizure NOS217
Elevated serum alkaline phosphatase (SAP)197
Death187
Depression173
Pruritus173
Polydipsia172
Lack of efficacy (bacteria) - NOS164
Polyuria163
Ataxia162
Elevated blood urea nitrogen (BUN)158
Weight loss156
Fever150
Anaemia NOS149
Decreased appetite143
Leucocytosis NOS134
Not eating127

Breeds named in reports

Retriever - Labrador480
Dog (unknown)400
Retriever - Golden225
Crossbred Canine/dog221
Shepherd Dog - German192
Shih Tzu125
Terrier - Bull - American Pit122
Boxer (German Boxer)117
Poodle (unspecified)111
Bulldog108
Terrier - Yorkshire88
Beagle84
Dachshund (unspecified)79
Pit Bull79
Spaniel - Cocker American74

Reported outcomes

Ongoing1,500
Recovered/Normal896
Outcome Unknown628
Died256
Euthanized184
Recovered with Sequela45

Report a problem to FDA