Pet Recall Facts

Ingredients / Phenobarbital

Phenobarbital: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

1,657Total reports
1,525Dog reports
125Cat reports

FDA-approved products with this ingredient (Green Book)

All approved products with this ingredient, for any species.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

19991
20011
20021
20032
20041
20052
20062
20071
20081
20091
20103
201121
2012151
2013170
2014115
2015104
2016106
2017136
2018108
201993
202095
202185
202257
202376
2024140
2025124
202660

Species named in reports

Dog1,525
Cat125
Not given6
Other Canids1

Signs reported after Phenobarbital

Seizure NOS621
Lethargy (see also Central nervous system depression in Neurological)225
Vomiting168
Death by euthanasia118
Other abnormal test result NOS104
Lack of efficacy - NOS100
Ataxia97
Emesis93
Diarrhoea92
Death81
Anorexia76
Behavioural disorder NOS75
Elevated serum alkaline phosphatase (SAP)73
Elevated alanine aminotransferase (ALT)63
Increased seizure frequency62
Weight loss58
Lack of efficacy (ectoparasite) - flea55
Not eating50
Tremor44
Weakness42
Panting41
Vocalisation36
Decreased appetite35
Underdose33
Twitching33

Breeds named in reports

Dog (unknown)179
Retriever - Labrador140
Chihuahua94
Crossbred Canine/dog73
Domestic Shorthair71
Retriever - Golden68
Poodle (unspecified)62
Shepherd Dog - German62
Terrier - Yorkshire53
Beagle51
Shepherd Dog - Australian49
Shih Tzu43
Dachshund (unspecified)41
Maltese37
Siberian Husky35

Reported outcomes

Recovered/Normal495
Ongoing480
Outcome Unknown397
Euthanized112
Died88
Recovered with Sequela65

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