Ingredients / S-Methoprene

S-Methoprene: FDA adverse event reports for pets

Reports received through June 26, 2026. Data and limitations.

FDA-approved products with this ingredient (Green Book)

No matching Green Book entry is supplied in this dataset. This alone does not establish regulatory status.

EPA-registered pesticide. Flea and tick products with this ingredient, such as many collars, spot-ons and shampoos, are registered by the U.S. Environmental Protection Agency (EPA), not approved by FDA, so they have no FDA Green Book record. Pet owners still send reports about them to FDA, and those reports are counted here. Questions about these products: National Pesticide Information Center.

Brand names come only from the Green Book. Brand names in FDA's public report data are masked, so counts cannot be attributed to any brand. Ingredient names in the reports are written many ways; we group them under one ingredient name and count each report once per ingredient (method).

Reports by year received

Species named in reports

Signs reported after S-Methoprene

Breeds named in reports

Reported outcomes

Report a problem to FDA